Uses & Applications
Lethal Gene/Cytotoxic Agent
- Delivery of lethal genes (e.g., p53, HSV-tk, etc.)
- Delivery of cytotoxic chemotherapeutic agents to cytoplasm or membrane of target cells.
Antigen Presentation/Phenotypic Transformation
- Elicit innate immune response (IL-12, IL-6 etc…)
- Transforms phenotype of cell (e.g. making cells HER-2 +)
Necrosis and Apoptosis
Efficient Cell Manufacturing
Cell specific Zip-Codes freely float in the blood of patients and can be captured to diagnosis the presence of cancer, monitor therapeutic response or to screen for cancers. Zip-Codes offer the opportunity for highly specific and very low detection levels as diagnostic tools. Zip-Codes are isolated from the blood, can be detected using PCR or other sequencing technologies and can be detected individually or on an array.